Six world-class research teams focus on new frontiers in metabolism

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The Azrieli Foundation, the Canadian Institutes of Health Research (CIHR), the International Development Research Center (IDRC), and the Israel Science Foundation (ISF) are pleased to announce the recipients of the 5and call for proposals. These world-class research teams will focus on new frontiers in metabolism.

Selected from 44 proposals, the six winning teams will receive funding totaling up to CAD 7 million over the next three years. The awarded researchers are based at leading institutions in Canada and Israel and will include 14 researchers and trainees based in six developing countries.

Much remains to be learned about the biological causes of metabolic diseases, such as type 2 diabetes. According to the World Health Organization (WHO), metabolic syndrome is defined as a medical condition characterized by abdominal obesity, insulin resistance, hypertension, type 2 diabetes, coronary heart disease, stroke and other disabilities. Over the past two decades, there has been a striking increase in the incidence of metabolic syndrome and other metabolic disorders worldwide, and particularly in developing countries. The two fundamental forces that propagate this syndrome are the increase in the consumption of fast food high in calories and low in fiber and the decrease in physical activity due to mechanized transport and the sedentary lifestyle of leisure and work. In addition, millions of people face a double health burden that represents a troubling modern-day paradox: the impact of poverty-related diseases associated with infections and undernutrition is exacerbated by the emerging epidemic of metabolic diseases , which are associated with increasing wealth. .

Using state-of-the-art technologies, research teams will study the biological mechanisms underlying the prevailing metabolic conditions. The research will advance our understanding of the influence of factors such as the microbiome or circadian rhythms on the human metabolic system. Research results from these projects may expand treatment options for these conditions.

The Canadian and Israeli teams will include researchers from Brazil, Thailand, Argentina, Cameroon, Colombia and Mexico. As collaborators or trainees, these researchers will contribute to and benefit from their involvement in the program with the overall aim of strengthening their country’s research capacity, promoting research excellence and building lasting international scientific collaborations.

Source:

Canadian Institutes of Health Research (CIHR)

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